At this point, vaccines on their own aren’t going to be enough to prevent our health-care system from collapsing, but vaccinating Ontarians is still the best way to get out of the pandemic in the long term, to restore Ontario’s economy, and to stop worrying about lockdowns. 41 If 95% of people experience Covid-19 virtually symptom-free, the risk of exposure to an untested vaccine is irresponsible. An open letter to all health care professionals: First, thank you. Open Letter from Christian Leaders to the Prime Minister Concerning Vaccine Passport Proposals August, 2021 In July 2021, the Prime Minister Boris Johnson and the Vaccines Minister Nadhim Zahawi at different points announced the introduction in September of vaccine passports for nightclubs and “other crowded venues”. Twelve grim months later, nothing is the same. They are a global public health good. Found insideReich has been following the issue of vaccine refusal for over a decade, and examines how parents who opt out of vaccinations see their decision: what they fear, what they hope to control, and what they believe is in their child's best ... It isn't. From the Silent Generation to Baby Boomers, from Generation X to Millennials and Generation Z, we all have a stake in understanding the real story about Social Security. Penn State faculty and students have renewed calls for the university to require the COVID-19 vaccine, writing in separate open letters that the … SINGAPORE — Referring to an open letter by 12 doctors to parents questioning the long-term safety of the Pfizer-BioNTech Covid-19 vaccine for … Seventeen lawmakers sent an open letter Wednesday to Trinity Health, which owns more than 90 hospitals in 22 states, including seven MercyOne locations in Iowa. Faculty members at Western Michigan University are calling for a COVID-19 vaccine requirement this school year. Countering Geert Vanden Bossche’s dubious viral open letter warning against mass COVID-19 vaccination. A Letter to the Unvaccinated. The pandemic has claimed more than half a million lives in the United States. A Letter of Warning To FDA And Pfizer: On The Immunological Danger Of COVID-19 Vaccination In The Naturally Infected. June 21, ... It’s never been easier to get a COVID vaccine. Found insideVéase « Scientists were close to a coronavirus vaccine years ago . ... [ 47 ] « Open letter to CEPI Board Members : Revise CEPI's access policy » ... If you appreciate us bringing you the other side of the story, even regarding forbidden topics like adverse reactions to COVID-19 vaccines, please subscribe to our exclusive content at RebelNews+, which also supports the work that we do. A COVID-19 Vaccination Record Card from the CDC (Centers for Disease Control and Prevention) with two syringes a bottle of COVID-19 vaccine and a vial of saline. Penn State faculty and students have renewed calls for the university to require the COVID-19 vaccine, writing in separate open letters that the … Alabama’s health sector in open letter urges COVID-19 vaccinations “The benefits of getting vaccinated FAR outweigh any potential risk,” the letter reads. An open letter from an attorney and microbiologist to the New Zealand government titled "Lawyer's Open Letter to NZ Government on COVID Vaccine Crimes" was posted on June 8, … Found insideMahase , E 2020 , Covid - 19 : Russia Approves Vaccine without Large ... Open COVID Pledge 2020 , Frequently Asked Questions , viewed 28 September 2020 ... The COVID-19 vaccines help reduce the spread of the virus, therefore decreasing the likelihood that it will mutate and create new variants. Found insideThe letter calls for assurance that a vaccine for the virus will be provided ... It looks like the coronavirus is being weaponized as yet another element to ... His argument sounds a lot like an argument Andrew Wakefield once made for MMR. Found inside – Page 316Corona/COVID-19, Measles, Swine Flu, Cervical Cancer, Avian Flu, SARS, BSE, ... the aforementioned Angela Spelsberg) to write an open letter to the North ... The key is the dinosaur's genetic code that lives on in modern birds- even chickens. From cutting-edge biology labs to field digs underneath the Montana sun, How to Build a Dinosaur explains and enlightens an awesome new science. Vaccine Choice Canada. Humanity today, in all its fragility, is searching for an effective and safe vaccine against COVID-19. COVID-19 Vaccine: An Open Letter to Our California University Communities To: Our students, faculty colleagues, and all others who help make our universities some of the greatest purveyors of … written by James Thornton August 4, 2021. Found inside... Against COVID-19, UNAIDS, (14 May 2020), https://www.unaids.org/en/resources/presscentre/featurestories/2020/may/20200514_covid19vaccine-open-letter. This intense new novel follows a middle-aged man as he contends with a past he has never much thought about—until his closest childhood friends return with a vengeance, one of them from the grave, another maddeningly present. Open letter flags results that appear to be duplicated and calls for access to the underlying data on the first COVID-19 vaccine to be approved for widespread use. The Association of American Physicians and Surgeons has published an open letter calling on universities to not mandate students take the COVID vaccine. Former world leaders urge Biden to waive COVID vaccine patents. The open letter by the 12 doctors claimed the following: The open letter was posted by a doctor, Dr Kho Kwang Po. Severe COVID infection is preventable with vaccines. Geert Vanden Bossche is a scientist who published an open letter warning of global catastrophe due to deadly variants of COVID-19 selected for by mass vaccination. An open letter to Boris Johnson signed by more than 1,250 clergy from different Christian denominations across the UK says the “introduction of vaccine passports would constitute an … As they describe such trials: “Human challenge trials deliberately expose participants to infection, in order to study diseases and test vaccines or treatments.They have been used for influenza, malaria, typhoid, dengue fever, and cholera. An Open Letter on Global COVID-19 Vaccine Equity March 3rd, 2021 An open letter to President Biden, and leaders of the US pharmaceutical industry, On February 24th, 2021, Ghana received the first shipment of COVID-19 vaccine secured by COVAX, the World Health Organization’s facility for global vaccine distribution. Earlier in May, Chia, Yang and Kho were part of a group of 12 doctors who wrote an open letter addressing parents and asking them to carefully … ... has written an open letter to the university’s president and the provost. Found inside – Page iIn some ways a sequel to Nahin's An Imaginary Tale, this book examines the many applications of complex numbers alongside intriguing stories from the history of mathematics. Senior and local New Mexico elected officials sent an open letter to state business leaders and commercial associations on Friday encouraging vaccination policies for employees and patrons that can help stem the rising tide of increased COVID-19 infections and hospitalizations. Global South Against Xenophobia (GSAX) of the COVID-19 People’s Coalition, Lawyers for Human Rights (LHR) and the South African Human Rights Defenders Network (SAHRDN) have written an open letter to President Cyril Ramaphosa asking that government reveal its vaccine rollout strategy. Dear Colleagues, The recent announcement that the United States Trade Representative will discuss options to waive some COVID-19 vaccine intellectual property (IP) rights has created some confusion to the world. OPEN LETTER: Uniting Behind A People’s Vaccine Against COVID-19. OCLA researcher Dr. Denis Rancourt and several fellow Canadian academics penned an open letter to support those who have decided not to accept the COVID-19 vaccine. A group of Black doctors wrote a "love letter" to Black America about historical skepticism of vaccines and medical experimentation to encourage taking the Covid-19 vaccine. Defining the field of global health law, Lawrence Gostin drives home the need for effective governance and offers a blueprint for reform, based on the principle that the opportunity to live a healthy life is a basic human right. Dr. Bonnie Henry, British Columbia Provincial Health Officer Ministry of Health 1515 Blanchard Street Victoria, BC, V8W 3C9. Found inside – Page 109... hundreds of millions of doses of a COVID-19 vaccine by the end of 2020. ... Nearly 2,000 former DOJ officials signed an open letter in May calling for ... The theme of reaffirming and encouraging our youth and black girls and women does not go unnoticed and while this collection of work is clearly a window into the maturation of one man - it is also a snapshot of the shared feelings of many ... More than 2,200 Oregonians have died with the coronavirus. The letter demands a university-wide vaccination requirement, noting that the majority of the Big Ten already plans to use one.According to the letter, Penn State was among the top universities for coronavirus cases in the 2020-21 academic year. Found insideThis book brings together many of the world's leading scientists researching aluminium and life and contains their critical summaries on the known facts about aluminium toxicity in man and to offer an opinion on the implications of this ... Found insideThe Inside Story of India's Fight against COVID-19 Abantika Ghosh ... Bucci, Enrico, 'Note of concern: Open Letter to DY Logunov et al.,', ... Found inside – Page 16Secondly, no successful vaccine against any coronavirus has been produced so ... the British Society for Immunology published an open letter stating that it ... According to UDOH’s dashboard Monday, 62% of Utahns 12 and older — the age groups eligible to get a COVID-19 vaccine — have received at least one … Open Letter to Dr. Bonnie Henry from BC Physician re: Moderna Vaccine Reactions. Worsening mass illness and deaths, a preventable humanitarian catastrophe, are destabilizing, and projected to increase. Those who … ... Australia's top doctors have signed an open letter … Humanity today, in all its fragility, is searching for an effective and safe vaccine against COVID-19. Available in: Found insideJosh Nathan-Kazis, “Johnson & Johnson Says Its Coronavirus Vaccine Could Be Ready ... James Love, “Open Letter Asking 37 WTO Members to Declare Themselves ... From the #1 New York Times bestselling author of The Handmaid's Tale In this final volume of the internationally celebrated MaddAddam trilogy, the Waterless Flood pandemic has wiped out most of the population. American expats to US government: give us vaccines! On a global scale, 700 000 cases of damage or death are expected as a result of the vaccine. This stance encompasses vaccines in the same way as therapeutics. A COVID-19 Vaccination Record Card from the CDC (Centers for Disease Control and Prevention) with two syringes a bottle of COVID-19 vaccine and a vial of saline. Urgent action is … There are hundreds of locations, including many that take walk-ins and have evening and weekend hours. Severe COVID infection is preventable with vaccines. 41 If 95% of people experience Covid-19 virtually symptom-free, the risk of exposure to an untested vaccine is irresponsible. COVID-19 vaccineiStock. It is our best hope of putting a stop to this painful global pandemic. OUR SCIENCE / An Open Letter to COVID-19 Vaccine Trial Participants from Albert Bourla, Chairman and CEO Dear Participant, Today, Pfizer and BioNTech announced the results of the first interim analysis from our COVID-19 vaccine study. Experts say Covid … Move for some health care systems to require COVID-19 vaccine comes in midst of nurse shortage. Found inside... you find yourself siding with in the opening story about Tim's open letter to ... numbers of Americans vaccinated for COVID-19 to achieve herd immunity? We note that a wide range of si d e effects is being reported following vaccination of previously healthy younger individuals with the gene-based COVID-19 vaccines. JULY 2021 To whom it may concern, We offer this letter in support of Professor Bridle’s exemplary character and scientific intellect, and, most importantly, his right to express his scientific opinions freely and unfettered.… All of us have felt their loss. The role of the media and the official communication plan. An Open Letter to COVID-19 Vaccine Trial Participants from Albert Bourla, Chairman and CEO. An Open Letter from Pfizer Chairman and CEO to Colleagues. You can also read Dr. Hoffe's open letter directed to Dr. Bonnie Henry at the bottom of this page. As of yesterday, it’s been one year since the first case of COVID-19 was diagnosed in Oregon. Found insideThis book includes fifty low-carb keto meal prep recipes, each containing two or three components you can mix and match to create more than 125 delicious combinations. By NG JUN SEN. For more news and specials on immunization and vaccines visit the Pink Book's Facebook fan page Bossche says the COVID vaccines approved so far have been developed by “just brilliant” people and he has no criticism of them But, as he tells Dr. Phillip McMillan in an interview, “please use the right vaccine at the right place. This 2020 edition includes: · Country-specific risk guidelines for yellow fever and malaria, including expert recommendations and 26 detailed, country-level maps · Detailed maps showing distribution of travel-related illnesses, including ... In an open letter shared by Oxfam on Wednesday, ... the letter reads, as public health experts have … SINGAPORE, May 23 — Referring to an open letter by 12 doctors to parents questioning the long-term safety of the Pfizer-BioNTech Covid-19 vaccine for use on children, Senior Minister of State for Health Koh Poh Koon said he was “aghast and disappointed” by the doctors’ conduct. Found insidethe - making - what - will - happen - with - a - rushed - covid - 19 - vaccine / » [ ... ] are scientifically challenging and have a unique potential safety ... Last week the discussion of COVID vaccination burst into the news and ripped the scab right off the wound exposing the divide among Alabamians about whether to vaccinate or not. Doctors and scientists wrote an urgent open letter to the European Medicines Agency on March 10th, warning of COVID-19 vaccine dangers and called on the European Medicines Agency (EMA) to answer urgent safety questions regarding the vaccines, or withdraw the vaccines’ … 93 doctors have signed a joint letter of protest calling to refrain from administering Covid-19 vaccines to children. OPEN LETTER: Uniting Behind A People’s Vaccine Against COVID-19. Brown said the proposal would cost 30p per person per week in the UK. Yesterday, 1 Day Sooner posted this Open Letter calling for human challenge vaccine trials for Covid-19. Found inside – Page 159... a people's vaccine against COVID-19”, https://www.unaids. org/en/resources/presscentre/featurestories/2020/may/20200514_covid19-vaccine-open-letter/. This year, health care professionals have sacrificed much to care for many, fighting COVID-19 skillfully, bravely and tirelessly. An open letter from the group recommends that private companies, which employ 124 million Americans, require staff to get vaccinated, and offers guidance if they choose not to. On a global scale, 700 000 cases of damage or death are expected as a result of the vaccine. "As vaccine coverage has changed the nature of the province-wide risk of COVID-19, it is time, in my opinion, to shift from province-wide extraordinary measures to … Dr. Charles D. Hoffe, BSc, MB, BCh, LMCC Lytton Medical Clinic Lytton BC V0K 1Z0. The comedian and actor said people should "trust the … A treatise on why the American medical care system fails to function like a marketplace system, and how to make it so. It was addressed to Professor Benjamin Ong, chairman of the expert committee. Found inside“L.A. County Jail Inmates Trying to Infect Themselves with Coronavirus, Sheriff Says. ... featurestories/2020/may/20200514_covid19-vaccine-open-letter. age limit for covid vaccine. Open Letter to the WHO: Immediately Halt All Covid-19 Mass Vaccinations (Geert Vanden Bossche, DMV, PhD) chiricaspi Coronavirus March 6, 2021 May 4, 2021 13 Minutes Geert Vanden Bossche, DMV, PhD, independent virologist and vaccine expert, formerly employed at GAVI and The Bill & Melinda Gates Foundation. Found insideAt an internment camp in Indonesia, forty-seven people are pronounced dead with acute hemorrhagic fever. Dear Volunteer, Clinical trials of COVID-19 vaccinations are critical for responding to COVID-19. Found inside – Page 482017) showed that WHO's popular DTP vaccine is killing more African children than the diseases it prevents. ... In the meantime, an open Letter from ... 5 April, 2021. There are virtually no … They want global action on Covid… With the visit of US Deputy Secretary of State Wendy R. Sherman, a collection of high-profile American expats living in Thailand released an open letter asking for Covid-19 vaccines. Some doctors and cardiologists here have written an open letter appealing to the Expert Committee on Covid-19 Vaccination to halt the vaccination … Found inside – Page 183[2] Mancini, D. et M. Peel (2020), « « Vaccine nationalism » delays WHO's ... -general-s-opening-remarks-at-the-media-briefing-on-covid-19---2-october-2020. With Covid-19 infections rising in Thailand and bad news after bad news after bad news coming out of the vaccine supply and distribution chains, the managing director of AstraZeneca Thailand penned an open letter to the people of Thailand today. An open letter to health care workers on taking the COVID-19 vaccine. It is our best hope of putting a stop to this painful global pandemic. An open letter from Intrepid Travel’s CEO: For travel to return, we need global vaccine equity. Found insideVulture: “Reading this novel is like holding a live wire in your hand.” Time: “One of the most celebrated novels of the year.” Marie Claire: “You won't be able to put it down.” Bustle: “The book everyone is talking about.” ... A People’s Vaccine — Free and Fair for All — to End the COVID-19 Crisis. OPEN LETTER. Download the Letter The unprecedented wave of COVID-19 now engulfing India, Brazil, and other nations—and the extreme and widening global inequities in access to vaccines—test our collective conscience and threaten our national security. Found inside – Page 441Includes - COVID-19 THE UN-TOLD STORY Part 2 Rui Alexandre Gabirro ... in “Open letter from medical doctors and health professionals to all Belgian ... Reply to open letter concerning the transparency and evaluation of vaccines for COVID-19. The letter lists 15 … vaccine inputs by providing financial and technical assistance, and facilitating private sector licensing and knowledge transfer, including for mRNA platform vaccines, to ramp up vaccine manufacturing capabilities in Africa, Latin America, and Asia; and by reaching a global agreement on reducing the use of export restrictions for COVID-19 vaccines, KNOXVILLE, Tenn. (WATE) – Republicans in the Tennessee Senate have signed an open letter urging Tennesseans to get a COVID-19 vaccine as cases spike across the country. Found insideThe aim of this Maternal Immunization book is to provide a contemporary overview of vaccines used in pregnancy (and the lactation period), with emphasis on aspects of importance for the target groups, namely, rationale for the use of ... COVID-19 vaccineiStock. By contrast, less than one percent have been administered in low-income countries. Sir Lenny Henry has written an open letter urging black Britons to take the Covid-19 vaccine. An open letter to the American public on COVID-19 vaccines. The freedom coveted by some Americans to avoid vaccines and spurn masks is, increasingly, leading to a group of Americans that can't access vaccines getting Covid-19. The Liberty Beacon Urgent Open Letter from Doctors and Scientists to the European Medicines Agency regarding COVID-19 Vaccine Safety Concerns DOCTORS FOR COVID ETHICS Emer Cooke, Executive Director, European Medicines Agency, Amsterdam, The Netherlands Found insideTHE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel ... Found insideThe explosive, behind-the-scenes story of Donald Trump’s high-stakes confrontation with Beijing, from an award-winning Washington Post columnist and peerless observer of the U.S.–China relationship There was no calm before the storm. Found insideThe following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. Found insideApplied Economics Letters, 1–6. ... A. andNicolau, J. (2020) An open market valuation of the effects of Covid-19 on the travel and tourism industry. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. In this meticulously reported book, Alex Berenson, a former New York Times reporter, explodes those myths, explaining that almost no one is in prison for marijuana; a tiny fraction of doctors write most authorizations for medical marijuana, ... The comedian and actor said people should "trust the … Infectious diseases expert slams open letter by 5 doctors for misleading public on Covid-19 vaccines for youth. This public letter to President Biden was updated on February 23, 2021 with new signers, now totaling 223. Humanity today, in all its fragility, is searching for an effective and safe vaccine against COVID-19. An open letter on vaccine dose donations The G7 Summit is a vital opportunity for G7 leaders to agree the actions that will get COVID-19 vaccines where they are most needed, fast. Posted on August 2, 2021 by admin. An open letter from the Acting Health Commissioner to Philadelphia about the COVID Delta variant. To do this, Stuck provides a clear-eyed examination of the social vectors that transmit vaccine rumors, their manifestations around the globe, and how these individual threads are all connected. “This decision to terminate nurses and other healthcare professionals who do not take the vaccine will only exacerbate the problem. Letter from the chairs of EMA's Management Board to Guido Rasi at the end of his term as EMA's Executive Director. Open Letter to Oregon: OHA Director Patrick Allen thanks Oregonians. Image courtesy: iStock. Infectious diseases expert slams open letter by five Singapore doctors for ‘misleading’ public on Covid-19 vaccines for youth Monday, 28 Jun 2021 10:27 PM MYT The doctors had asked for the vaccine rollout to be paused until 'more data' emerged on Pfizer's vaccine side-effects. The new memoir tracing story of cycling since the 1980s, through the eyes of Jonathan Vaughters, founder of team Education First and one of the sport's most towering figures. Jonathan Vaughters' story is the story of modern cycling. Sir Lenny Henry has written an open letter urging black Britons to take the Covid-19 vaccine. An open letter to the American people: Since the beginning of the COVID-19 pandemic, we have come together as physicians, nurses, and hospital and health system leaders to urge the American people to protect themselves, their neighbors and their loved ones amidst the worst global health crisis in generations. Among the vaccine letter’s signatories are Gordon Brown and Tony Blair. This letter asked officials to sup… In it, he gave a brief overview of the manufacturing process, the efforts made to supply more vaccines, and words of encouragement to the Thai public. Found insideThen try taradiddle. A Word for Every Day of the Year is a fascinating collection of 366 words and their definitions, perfect for anyone who loves the richness of the English language, its diversity and wants to expand their vocabulary. Blair County, Pa (WTAJ)- Governor Wolf and bipartisan COVID-19 vaccine Task Force sent a letter Thursday to ask local officials for help with the vaccine efforts. Found inside... and Selfishness Doomed the U.S. Coronavirus Response Andy Slavitt ... is so crucial during a vaccine trial was summarized in an open letter to Hahn ... Found insideBetween Two Fires chronicles the lives of a number of strivers who understand that their dreams are best—or only—realized through varying degrees of cooperation with the Russian government. Move for some health care systems to require COVID-19 vaccine comes in midst of nurse shortage. If you go to the Canadian Covid Care Alliance website, wwwcanadiancovidcarealliance.org you can sign this letter in support of Dr. Bridle. Published June … In an open letter directed to the Government, the group of 22 signatures stated 'things are very different as we enter the spring of 2021'. Found inside – Page 133... in an open letter published by The Lancet, disputed a conspiracy theory that the COVID-19 virus (coronavirus) is a bioweapon that was created in China ... The coronavirus vaccines … "We all assume we know what life is, but the more scientists learn about the living world-from protocells to brains, from zygotes to pandemic viruses-the harder they find it is to locate life's edge"-- Age Limit For COVID Vaccine Is Approved, But Open Letter Still Urges Halt. The professor said that while mandatory vaccination was not always considered the best option for the return to campus, the recent announcement of changes in COVID … We all know there can be tense moments among friends and family when the vaccine topic comes up, especially when there are differing opinions in the room. New Mexicans can schedule their vaccination at VaccineNM.org. The Affordable Care Act, landmark health legislation passed in 2010, called for the development of the National Prevention Strategy to realize the benefits of prevention for all Americans¿ health. A Victorian food manufacturer has become the first Australian company to mandate the Covid-19 vaccine among its employees. Found insideWhile a host of books have analyzed legal dimensions of LGBT public policy, this authoritative Routledge handbook is the first to utilize up-to-the-minute empirical data to examine and unpick the corrosive "post-factual" changes undermining ... 'This book gives plenty of examples of ad hominem attacks, intimidation, slander, threats of litigation, deception, dishonesty, lies and other violations of good scientific practice. On January 26, 2021, … Aug 03, 2021 at 12:30 PM. An open letter to fellow Christians: Please get the COVID-19 vaccine Church elder makes a biblical case for helping to end the pandemic. Jeffrey E. Sterling, MD, MPH, often finds himself with a little more extra time than everyone else-forty-eight hours a day, to be exact! Now Dr. Sterling shares his brilliant and easy-to-follow steps to increase efficiency. OPEN LETTER: Uniting Behind A People’s Vaccine Against COVID-19. Global South Against Xenophobia (GSAX) of the COVID-19 People’s Coalition, Lawyers for Human Rights (LHR) and the South African Human Rights Defenders Network (SAHRDN) have written an open letter to President Cyril Ramaphosa asking that government reveal its vaccine rollout strategy. The role of the media and the official communication plan. 93 doctors have signed a joint letter of protest calling to refrain from administering Covid-19 vaccines to children. Found inside“Many of the COVID 19 vaccines are not conventional vaccines. ... Carlo Maria Vigano, wrote an open letter (which over 100 million Americans have read) to ... “This decision to terminate nurses and other healthcare professionals who do not take the vaccine will only exacerbate the problem. Jewish doctors have warned the community against conspiracy theories claiming the Covid-19 vaccine causes infertility or contains products derived from pork. Shelton is one of 32 doctors, 100 nurses and 187 allied health professionals who have signed an open letter casting doubt on the Covid-19 vaccine, published on the NZDSOS website in … Phase One of the Covid-19 vaccination programme will shortly be completed, with every vulnerable adult in … At this point, vaccines on their own aren’t going to be enough to prevent our health-care system from collapsing, but vaccinating Ontarians is still the best way to get out of the pandemic in the long term, to restore Ontario’s economy, and to stop worrying about lockdowns. An Open Letter from Albert Bourla to Pfizer Employees. OPEN LETTER TO THE BIDEN-HARRIS ADMINISTRATION US Emergency Plan for Global COVID-19 Relief: ... To date, 82 percent of all COVID-19 vaccine doses that have gone into arms worldwide have been administered in high- and upper middle-income countries. 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